AN UNBIASED VIEW OF PHENOBARBITAL WEANING SCHEDULE NEWBORN

5. Phenytoin, sodium valproate, valproic acid: The effect of phenobarbital around the metabolism of phenytoin seems to get variable. Some investigators report an accelerating effect, even though others report no effect. Because the effect of phenobarbital on the metabolism of phenytoin is not really predictable, phenytoin and phenobarbital blood le